Andrew Truman, Ph.D.

Andrew Truman, Ph.D.

Professor
Biological Sciences

Dr. Truman obtained his Ph.D. in Biochemistry at University College London, UK, where he uncovered the first Hsp90 interaction regulated by client phosphorylation (Mpk1). As a postdoctoral researcher at Johns Hopkins University and Boston University with Dr. David E. Levin, Dr. Truman explored the novel ways phosphorylation can shape kinase activity and specificity. As a Research Assistant Professor at the University of Chicago under the mentorship of Dr. Stephen Kron he published the first detailed study on Hsp70 phosphorylation in Cell. In 2015, he established his research lab at the University of North Carolina at Charlotte, was promoted to Associate Professor with Tenure in 2021 and Full Professor in June 2024. His current research focus is understanding the Chaperone Code, the myriad of post-translational modifications that impact the function of the Hsp70 molecular chaperone. He has authored 61 papers in journals that include Cell, Molecular Cell, Cell Reports, PLOS Biology, PLOS Genetics and Journal of Biological Chemistry. Dr. Truman is currently funded by NIH 2 R01s, an R21 and R15 grants as PI in addition to another R01 and R15 as co-investigator. He is a Fellow of the Cell Stress Society (FSSI) and is a Senior Editor for Cell Stress and Chaperones and Journal of Biological Chemistry. In September 2022, he was awarded the Ferruccio Ritossa Award by Cell Stress Society International (CSSI) for his work in understanding the interplay between chaperones and proteins involved in signal transduction. In 2023, Dr. Truman established and now leads the Charlotte Group for Proteostasis Research. Dr. Truman is an avid mountain biker and spends his weekends tackling some of the toughest (and most fun!) trails in the North Carolina countryside.rm complex trait evolution?